Files
reactics/examples/smt/heat_shock_response.py
Artur Meski af26ca543b Examples and clean-ups (#1)
- Attempt at implementing an example for DRS
- Complete reactions set
- New automaton
- Formula
- Fixed automaton scaling
- Proc index in the formula
- Benchmark generators
- Scripts to reproduce experiments for reaction mining
2023-11-06 21:09:08 +00:00

134 lines
4.8 KiB
Python
Executable File

#!/usr/bin/env python
#
# Copyright (c) 2015-2019 Artur Meski
#
# Permission is hereby granted, free of charge, to any person obtaining a copy
# of this software and associated documentation files (the "Software"), to deal
# in the Software without restriction, including without limitation the rights
# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
# copies of the Software, and to permit persons to whom the Software is
# furnished to do so, subject to the following conditions:
#
# The above copyright notice and this permission notice shall be included in all
# copies or substantial portions of the Software.
#
# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
# SOFTWARE.
#
from rs import *
from smt import *
import sys
import resource
def heat_shock_response(print_system=True, verify_rsc=True):
if len(sys.argv) < 1 + 1:
print("{source} <type>".format(source=sys.argv[0]))
print("type:")
print(" - 1 -- RSC")
print(" - 0 -- RSC translated into RS")
print()
exit(1)
verify_rsc = bool(int(sys.argv[1]))
stress_temp = 42
max_temp = 50
r = ReactionSystemWithConcentrations()
r.add_bg_set_entity(("hsp", 1))
r.add_bg_set_entity(("hsf", 1))
r.add_bg_set_entity(("hsf2", 1))
r.add_bg_set_entity(("hsf3", 1))
r.add_bg_set_entity(("hse", 1))
r.add_bg_set_entity(("mfp", 1))
r.add_bg_set_entity(("prot", 1))
r.add_bg_set_entity(("hsf3:hse", 1))
r.add_bg_set_entity(("hsp:mfp", 1))
r.add_bg_set_entity(("hsp:hsf", 1))
r.add_bg_set_entity(("temp", max_temp))
r.add_bg_set_entity(("heat", 1))
r.add_bg_set_entity(("cool", 1))
r.add_reaction([("hsf", 1)], [("hsp", 1)], [("hsf3", 1)])
r.add_reaction([("hsf", 1), ("hsp", 1), ("mfp", 1)], [], [("hsf3", 1)])
r.add_reaction([("hsf3", 1)], [("hse", 1), ("hsp", 1)], [("hsf", 1)])
r.add_reaction([("hsf3", 1), ("hsp", 1), ("mfp", 1)], [("hse", 1)], [("hsf", 1)])
r.add_reaction([("hsf3", 1), ("hse", 1)], [("hsp", 1)], [("hsf3:hse", 1)])
r.add_reaction(
[("hsp", 1), ("hsf3", 1), ("mfp", 1), ("hse", 1)], [], [("hsf3:hse", 1)]
)
r.add_reaction([("hse", 1)], [("hsf3", 1)], [("hse", 1)])
r.add_reaction([("hsp", 1), ("hsf3", 1), ("hse", 1)], [("mfp", 1)], [("hse", 1)])
r.add_reaction([("hsf3:hse", 1)], [("hsp", 1)], [("hsp", 1), ("hsf3:hse", 1)])
r.add_reaction(
[("hsp", 1), ("mfp", 1), ("hsf3:hse", 1)], [], [("hsp", 1), ("hsf3:hse", 1)]
)
r.add_reaction([("hsf", 1), ("hsp", 1)], [("mfp", 1)], [("hsp:hsf", 1)])
r.add_reaction(
[("hsp:hsf", 1), ("temp", stress_temp)], [], [("hsf", 1), ("hsp", 1)]
)
r.add_reaction([("hsp:hsf", 1)], [("temp", stress_temp)], [("hsp:hsf", 1)])
r.add_reaction(
[("hsp", 1), ("hsf3:hse", 1)], [("mfp", 1)], [("hse", 1), ("hsp:hsf", 1)]
)
r.add_reaction([("temp", stress_temp), ("prot", 1)], [], [("mfp", 1), ("prot", 1)])
r.add_reaction([("prot", 1)], [("temp", stress_temp)], [("prot", 1)])
r.add_reaction([("hsp", 1), ("mfp", 1)], [], [("hsp:mfp", 1)])
r.add_reaction([("mfp", 1)], [("hsp", 1)], [("mfp", 1)])
r.add_reaction([("hsp:mfp", 1)], [], [("hsp", 1), ("prot", 1)])
r.add_reaction_inc("temp", "heat", [("temp", 1)], [("temp", max_temp)])
r.add_reaction_dec("temp", "cool", [("temp", 1)], [])
r.add_permanency("temp", [("heat", 1), ("cool", 1)])
c = ContextAutomatonWithConcentrations(r)
c.add_init_state("0")
c.add_state("1")
c.add_transition("0", [("hsf", 1), ("prot", 1), ("hse", 1), ("temp", 35)], "1")
c.add_transition("1", [("cool", 1)], "1")
c.add_transition("1", [("heat", 1)], "1")
c.add_transition("1", [], "1")
rc = ReactionSystemWithAutomaton(r, c)
if print_system:
rc.show()
prop_req = [("mfp", 1)]
prop_block = []
prop = (prop_req, prop_block)
rs_prop = (state_translate_rsc2rs(prop_req), state_translate_rsc2rs(prop_block))
if verify_rsc:
smt_rsc = SmtCheckerRSC(rc)
smt_rsc.check_reachability(prop, max_level=40)
else:
orc = rc.get_ordinary_reaction_system_with_automaton()
if print_system:
print("\nTranslated:")
orc.show()
smt_tr_rs = SmtCheckerRS(orc)
smt_tr_rs.check_reachability(rs_prop)
def state_translate_rsc2rs(p):
return [e[0] + "#" + str(e[1]) for e in p]
def main():
heat_shock_response()
if __name__ == "__main__":
main()
# EOF